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P4HB Human Gene Knockout Kit (CRISPR)

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SKU
KN202275BN
P4HB - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "P4HB or NM_000918"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol P4HB
Locus ID 5034
Components

KN202275G1, P4HB gRNA vector 1 in pCas-Guide CRISPR vector

KN202275G2, P4HB gRNA vector 2 in pCas-Guide CRISPR vector

KN202275BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000918
UniProt ID P07237
Synonyms DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB
Summary This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
GA103363 P4HB CRISPRa kit - CRISPR gene activation of human prolyl 4-hydroxylase subunit beta 1 kit
$1,657.00
KN202275 P4HB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202275LP P4HB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202275RB P4HB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402275 P4HB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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