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Human P4HB activation kit by CRISPRa

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SKU
GA103363
P4HB CRISPRa kit - CRISPR gene activation of human prolyl 4-hydroxylase subunit beta
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA308403 Rabbit Polyclonal antibody to PDI (prolyl 4-hydroxylase, beta polypeptide)
100 ul
$665.00
RC202275 P4HB (Myc-DDK-tagged)-Human prolyl 4-hydroxylase, beta polypeptide (P4HB)
10 ug
$709.00

Other products for "P4HB"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol P4HB
Locus ID 5034
Components

GA103363G1, P4HB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103363G2, P4HB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103363G3, P4HB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000918
UniProt ID P07237
Synonyms DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB
Summary This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN202275 P4HB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202275BN P4HB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202275LP P4HB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202275RB P4HB - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402275 P4HB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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