DR4 (TNFRSF10A) Human Gene Knockout Kit (CRISPR)

SKU
KN202152BN
TNFRSF10A - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol DR4
Locus ID 8797
Components

KN202152G1, DR4 gRNA vector 1 in pCas-Guide CRISPR vector

KN202152G2, DR4 gRNA vector 2 in pCas-Guide CRISPR vector

KN202152BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_003844
UniProt ID O00220
Synonyms APO2; CD261; DR4; TRAILR-1; TRAILR1
Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA105843 TNFRSF10A CRISPRa kit - CRISPR gene activation of human TNF receptor superfamily member 10a 1 kit
$1,657.00
KN202152 TNFRSF10A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202152LP TNFRSF10A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202152RB TNFRSF10A - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402152 TNFRSF10A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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