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ASAH1 Human Gene Knockout Kit (CRISPR)

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SKU
KN202135LP
ASAH1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "ASAH1 or AK025211"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol ASAH1
Locus ID 427
Components

KN202135G1, ASAH1 gRNA vector 1 in pCas-Guide CRISPR vector

KN202135G2, ASAH1 gRNA vector 2 in pCas-Guide CRISPR vector

KN202135LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001127505, NM_004315, NM_177924, NM_001363743
UniProt ID Q13510
Synonyms AC; ACDase; ASAH; PHP; PHP32; SMAPME
Summary This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. provided by RefSeq, Oct 2015
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Other Versions
SKU Description Size Price
GA100309 ASAH1 CRISPRa kit - CRISPR gene activation of human N-acylsphingosine amidohydrolase 1 1 kit
$1,657.00
KN202135 ASAH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202135BN ASAH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202135RB ASAH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402135 ASAH1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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