Human ASAH1 activation kit by CRISPRa

SKU
GA100309
ASAH1 CRISPRa kit - CRISPR gene activation of human N-acylsphingosine amidohydrolase 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ASAH1
Locus ID 427
Components

GA100309G1, ASAH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100309G2, ASAH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100309G3, ASAH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001127505, NM_004315, NM_177924, NM_001363743
UniProt ID Q13510
Synonyms AC; ACDase; ASAH; PHP; PHP32; SMAPME
Summary This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. provided by RefSeq, Oct 2015
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Resources
Other Versions
SKU Description Size Price
KN202135 ASAH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202135BN ASAH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202135LP ASAH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202135RB ASAH1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402135 ASAH1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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