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PAM Human Gene Knockout Kit (CRISPR)

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SKU
KN202074LP
PAM - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "PAM or NM_000919"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol PAM
Locus ID 5066
Components

KN202074G1, PAM gRNA vector 1 in pCas-Guide CRISPR vector

KN202074G2, PAM gRNA vector 2 in pCas-Guide CRISPR vector

KN202074LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000919, NM_001177306, NM_001319943, NM_138766, NM_138821, NM_138822, NR_033440, NM_001364582, NM_001364584, NM_001364586, NM_001364588, NM_001364589, NM_001364590, NM_001364593, NM_001364583, NM_001364585, NM_001364587, NM_001364591, NM_001364592, NM_001364594, NR_157231
UniProt ID P19021
Synonyms PAL; PHM
Summary This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. provided by RefSeq, Jan 2016
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Documents
Resources
Other Versions
SKU Description Size Price
GA103382 PAM CRISPRa kit - CRISPR gene activation of human peptidylglycine alpha-amidating monooxygenase 1 kit
$1,657.00
KN202074 PAM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202074BN PAM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202074RB PAM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402074 PAM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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