Human PAM activation kit by CRISPRa

SKU
GA103382
PAM CRISPRa kit - CRISPR gene activation of human peptidylglycine alpha-amidating monooxygenase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PAM
Locus ID 5066
Components

GA103382G1, PAM gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103382G2, PAM gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103382G3, PAM gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000919, NM_001177306, NM_001319943, NM_138766, NM_138821, NM_138822, NR_033440, NM_001364582, NM_001364584, NM_001364586, NM_001364588, NM_001364589, NM_001364590, NM_001364593, NM_001364583, NM_001364585, NM_001364587, NM_001364591, NM_001364592, NM_001364594, NR_157231
UniProt ID P19021
Synonyms PAL; PHM
Summary This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. provided by RefSeq, Jan 2016
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN202074 PAM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202074BN PAM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202074LP PAM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN202074RB PAM - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402074 PAM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products