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EMP2 Human Gene Knockout Kit (CRISPR)

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SKU
KN201995RB
EMP2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "EMP2 or AK096403"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol EMP2
Locus ID 2013
Components

KN201995G1, EMP2 gRNA vector 1 in pCas-Guide CRISPR vector

KN201995G2, EMP2 gRNA vector 2 in pCas-Guide CRISPR vector

KN201995RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001424
UniProt ID P54851
Synonyms XMP
Summary This gene encodes a tetraspan protein of the PMP22/EMP family. The encoded protein regulates cell membrane composition. It has been associated with various functions including endocytosis, cell signaling, cell proliferation, cell migration, cell adhesion, cell death, cholesterol homeostasis, urinary albumin excretion, and embryo implantation. It is known to negatively regulate caveolin-1, a scaffolding protein which is the main component of the caveolae plasma membrane invaginations found in most cell types. Through activation of PTK2 it positively regulates vascular endothelial growth factor A. It also modulates the function of specific integrin isomers in the plasma membrane. Up-regulation of this gene has been linked to cancer progression in multiple different tissues. Mutations in this gene have been associated with nephrotic syndrome type 10 (NPHS10). provided by RefSeq, Mar 2015
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Documents
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Other Versions
SKU Description Size Price
GA101396 EMP2 CRISPRa kit - CRISPR gene activation of human epithelial membrane protein 2 1 kit
$1,657.00
KN201995 EMP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201995BN EMP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201995LP EMP2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401995 EMP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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