HDAC1 Human Gene Knockout Kit (CRISPR)
Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
|---|---|
| Vector | Luciferase-Puro |
| Target Symbol | HDAC1 |
| Locus ID | 3065 |
| Components |
KN201745G1, HDAC1 gRNA vector 1 in pCas-Guide CRISPR vector KN201745G2, HDAC1 gRNA vector 2 in pCas-Guide CRISPR vector KN201745LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_004964 |
| UniProt ID | Q13547 |
| Synonyms | GON-10; HD1; RPD3; RPD3L1 |
| Summary | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. provided by RefSeq, Jul 2008 |
| Shipping | Ambient |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| GA102088 | HDAC1 CRISPRa kit - CRISPR gene activation of human histone deacetylase 1 | 1 kit |
$1,657.00
|
|
| KN201745 | HDAC1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN201745BN | HDAC1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN201745RB | HDAC1 - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN401745 | HDAC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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