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CIRBP Human Gene Knockout Kit (CRISPR)

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SKU
KN201639LP
CIRBP - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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RC201639 CIRBP (Myc-DDK-tagged)-Human cold inducible RNA binding protein (CIRBP), transcript variant 1
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Other products for "CIRBP or AK094781"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol CIRBP
Locus ID 1153
Components

KN201639G1, CIRBP gRNA vector 1 in pCas-Guide CRISPR vector

KN201639G2, CIRBP gRNA vector 2 in pCas-Guide CRISPR vector

KN201639LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001280, NM_001300815, NM_001300829, NR_023312, NR_023313
UniProt ID Q14011
Synonyms CIRP
Summary Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3' UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
GA100827 CIRBP CRISPRa kit - CRISPR gene activation of human cold inducible RNA binding protein 1 kit
$1,657.00
KN201639 CIRBP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201639BN CIRBP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201639RB CIRBP - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401639 CIRBP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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