Human CIRBP activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | CIRBP |
| Locus ID | 1153 |
| Components |
GA100827G1, CIRBP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100827G2, CIRBP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100827G3, CIRBP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001280, NM_001300815, NM_001300829, NR_023312, NR_023313 |
| UniProt ID | Q14011 |
| Synonyms | CIRP |
| Summary | Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3' UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN201639 | CIRBP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN201639BN | CIRBP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN201639LP | CIRBP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN201639RB | CIRBP - human gene knockout kit via CRISPR, HDR mediated | 1 kit |
$1,657.00
|
|
| KN401639 | CIRBP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
|
|
Citations
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