NFIB Human Gene Knockout Kit (CRISPR)

SKU KN201590RB

NFIB - human gene knockout kit via CRISPR, HDR mediated

Product Data

• Format: 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
• Vector: RFP-BSD
• Target Symbol: NFIB
• Locus ID: 4781
• Components:

  KN201590G1, NFIB gRNA vector 1 in pCas-Guide CRISPR vector

  KN201590G2, NFIB gRNA vector 2 in pCas-Guide CRISPR vector

  KN201590RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001190737, NM_001190738, NM_001282787, NM_005596, NM_001369458, NM_001369459, NM_001369460, NM_001369463, NM_001369464, NM_001369465, NM_001369466, NM_001369467, NM_001369472, NM_001369473, NM_001369474, NM_001369475, NM_001369476, NM_001369480, NM_001369481, NR_161385, NM_001369461, NM_001369462, NM_001369468, NM_001369469, NM_001369470, NM_001369471, NM_001369477, NM_001369478, NM_001369479, NR_161382, NR_161383, NR_161384
• UniProt ID: O00712
• Synonyms: CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B; NFI-RED; NFIB2; NFIB3
• Summary: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.[UniProtKB/Swiss-Prot Function]
• Shipping: Ambient