Human NFIB activation kit by CRISPRa

SKU GA103188

NFIB CRISPRa kit - CRISPR gene activation of human nuclear factor I B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NFIB
• Locus ID: 4781
• Components:

  GA103188G1, NFIB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103188G2, NFIB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103188G3, NFIB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001190737, NM_001190738, NM_001282787, NM_005596, NM_001369458, NM_001369459, NM_001369460, NM_001369463, NM_001369464, NM_001369465, NM_001369466, NM_001369467, NM_001369472, NM_001369473, NM_001369474, NM_001369475, NM_001369476, NM_001369480, NM_001369481, NR_161385, NM_001369461, NM_001369462, NM_001369468, NM_001369469, NM_001369470, NM_001369471, NM_001369477, NM_001369478, NM_001369479, NR_161382, NR_161383, NR_161384
• UniProt ID: O00712
• Synonyms: CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B; NFI-RED; NFIB2; NFIB3
• Summary: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.[UniProtKB/Swiss-Prot Function]