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beta Arrestin 1 (ARRB1) Human Gene Knockout Kit (CRISPR)

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SKU
KN201279LP
ARRB1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "beta Arrestin 1 or BC003636"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol beta Arrestin 1
Locus ID 408
Components

KN201279G1, beta Arrestin 1 gRNA vector 1 in pCas-Guide CRISPR vector

KN201279G2, beta Arrestin 1 gRNA vector 2 in pCas-Guide CRISPR vector

KN201279LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004041, NM_020251
UniProt ID P49407
Synonyms ARB1; ARR1
Summary Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. provided by RefSeq, Jan 2011
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Documents
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Other Versions
SKU Description Size Price
GA100297 ARRB1 CRISPRa kit - CRISPR gene activation of human arrestin beta 1 1 kit
$1,657.00
KN201279 ARRB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201279BN ARRB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201279RB ARRB1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401279 ARRB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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