beta Arrestin 1 (ARRB1) Mouse Monoclonal Antibody [Clone ID: OTI2B3]
Specifications
| Product Data | |
| Clone Name | OTI2B3 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:500-2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human ARRB1 (NP_004032) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 47.1 kDa |
| Gene Name | arrestin beta 1 |
| Database Link | |
| Background | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. provided by RefSeq, Jan 2011. |
| Synonyms | ARB1; ARR1 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Chemokine signaling pathway, Endocytosis, MAPK signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2B3" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF812546 | Carrier-free (BSA/glycerol-free) ARRB1 mouse monoclonal antibody, clone OTI2B3 | 100 ug |
$620.00
|
|
| TA812546AM | ARRB1 mouse monoclonal antibody, clone OTI2B3, Biotinylated | 100 ul |
$509.00
|
|
| TA812546BM | ARRB1 mouse monoclonal antibody, clone OTI2B3, HRP conjugated | 100 ul |
$509.00
|
|
| TA812546S | ARRB1 mouse monoclonal antibody, clone OTI2B3 | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.