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APE1 (APEX1) Human Gene Knockout Kit (CRISPR)

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SKU
KN201208RB
APEX1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "APE1 or NM_001244249"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol APE1
Locus ID 328
Components

KN201208G1, APE1 gRNA vector 1 in pCas-Guide CRISPR vector

KN201208G2, APE1 gRNA vector 2 in pCas-Guide CRISPR vector

KN201208RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001244249, NM_001641, NM_080648, NM_080649
UniProt ID P27695
Synonyms APE; APE1; APEN; APEX; APX; HAP1; REF1
Summary The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.provided by RefSeq, Dec 2019
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Other Versions
SKU Description Size Price
GA100229 APEX1 CRISPRa kit - CRISPR gene activation of human apurinic/apyrimidinic endodeoxyribonuclease 1 1 kit
$1,657.00
KN201208 APEX1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201208BN APEX1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201208LP APEX1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401208 APEX1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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