GLI1 Human Gene Knockout Kit (CRISPR)

SKU
KN201110RB
GLI1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol GLI1
Locus ID 2735
Components

KN201110G1, GLI1 gRNA vector 1 in pCas-Guide CRISPR vector

KN201110G2, GLI1 gRNA vector 2 in pCas-Guide CRISPR vector

KN201110RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001160045, NM_001167609, NM_005269
UniProt ID P08151
Synonyms GLI
Summary This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, May 2009
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Other Versions
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GA101822 GLI1 CRISPRa kit - CRISPR gene activation of human GLI family zinc finger 1 1 kit
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KN201110 GLI1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN201110BN GLI1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN201110LP GLI1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN401110 GLI1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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