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CBARA1 (MICU1) Human Gene Knockout Kit (CRISPR)

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SKU
KN200921LP
MICU1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC200921 MICU1 (Myc-DDK-tagged)-Human calcium binding atopy-related autoantigen 1 (CBARA1), nuclear gene encoding mitochondrial protein, transcript variant 1
10 ug
$289.00 $457.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
10 ug
$470.00
TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
20 ul
$265.00

Other products for "CBARA1 or NM_001195518"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector Luciferase-Puro
Target Symbol CBARA1
Locus ID 10367
Components

KN200921G1, CBARA1 gRNA vector 1 in pCas-Guide CRISPR vector

KN200921G2, CBARA1 gRNA vector 2 in pCas-Guide CRISPR vector

KN200921LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001195518, NM_001195519, NM_006077, NM_001363513
UniProt ID Q9BPX6
Synonyms CALC; CBARA1; EFHA3; MPXPS
Summary This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq, Mar 2013
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Documents
Resources
Other Versions
SKU Description Size Price
GA107063 MICU1 CRISPRa kit - CRISPR gene activation of human mitochondrial calcium uptake 1 1 kit
$1,657.00
KN200921 MICU1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200921BN MICU1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200921RB MICU1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400921 MICU1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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