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LZTS2 Human Gene Knockout Kit (CRISPR)

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SKU
KN200824BN
LZTS2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "LZTS2 or NM_001318099"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol LZTS2
Locus ID 84445
Components

KN200824G1, LZTS2 gRNA vector 1 in pCas-Guide CRISPR vector

KN200824G2, LZTS2 gRNA vector 2 in pCas-Guide CRISPR vector

KN200824BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001318099, NM_001318100, NM_001318101, NM_032429
UniProt ID Q9BRK4
Synonyms LAPSER1
Summary The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, Dec 2015
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Documents
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Other Versions
SKU Description Size Price
GA113550 LZTS2 CRISPRa kit - CRISPR gene activation of human leucine zipper tumor suppressor 2 1 kit
$1,657.00
KN200824 LZTS2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200824LP LZTS2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200824RB LZTS2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400824 LZTS2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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