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NQO1 Human Gene Knockout Kit (CRISPR)

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SKU
KN200620BN
NQO1 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "NQO1 or BC000906"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol NQO1
Locus ID 1728
Components

KN200620G1, NQO1 gRNA vector 1 in pCas-Guide CRISPR vector

KN200620G2, NQO1 gRNA vector 2 in pCas-Guide CRISPR vector

KN200620BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000903, NM_001025433, NM_001025434, NM_001286137
UniProt ID P15559
Synonyms DHQU; DIA4; DTD; NMOR1; NMORI; QR1
Summary This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA101198 NQO1 CRISPRa kit - CRISPR gene activation of human NAD(P)H quinone dehydrogenase 1 1 kit
$1,657.00
KN200620 NQO1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200620LP NQO1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200620RB NQO1 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400620 NQO1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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