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HDAC3 Human Gene Knockout Kit (CRISPR)

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SKU
KN200605RB
HDAC3 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (4)

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Other products for "HDAC3 or NM_003883"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol HDAC3
Locus ID 8841
Components

KN200605G1, HDAC3 gRNA vector 1 in pCas-Guide CRISPR vector

KN200605G2, HDAC3 gRNA vector 2 in pCas-Guide CRISPR vector

KN200605RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_003883, NM_001355039, NM_001355040, NM_001355041, NR_149164, NR_149165, NR_149166, NR_149167, NR_149168, NR_149169
UniProt ID O15379
Synonyms HD3; RPD3; RPD3-2
Summary Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
GA105883 HDAC3 CRISPRa kit - CRISPR gene activation of human histone deacetylase 3 1 kit
$1,657.00
KN200605 HDAC3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200605BN HDAC3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200605LP HDAC3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400605 HDAC3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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