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APEX2 Human Gene Knockout Kit (CRISPR)

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SKU
KN200320RB
APEX2 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "APEX2 or NM_001271748"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Vector RFP-BSD
Target Symbol APEX2
Locus ID 27301
Components

KN200320G1, APEX2 gRNA vector 1 in pCas-Guide CRISPR vector

KN200320G2, APEX2 gRNA vector 2 in pCas-Guide CRISPR vector

KN200320RBD, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001271748, NM_014481
UniProt ID Q9UBZ4
Synonyms APE2; APEXL2; XTH2; ZGRF2
Summary Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Nov 2012
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Documents
Resources
Other Versions
SKU Description Size Price
GA109110 APEX2 CRISPRa kit - CRISPR gene activation of human apurinic/apyrimidinic endodeoxyribonuclease 2 1 kit
$1,657.00
KN200320 APEX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200320BN APEX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200320LP APEX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400320 APEX2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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