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Human APEX2 activation kit by CRISPRa

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SKU
GA109110
APEX2 CRISPRa kit - CRISPR gene activation of human apurinic/apyrimidinic endodeoxyribonuclease 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA358877 APEX2 Antibody - C-terminal region
100 ul
$585.00
RC200320 APEX2 (Myc-DDK-tagged)-Human APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2), nuclear gene encoding mitochondrial protein
10 ug
$482.00

Other products for "APEX2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol APEX2
Locus ID 27301
Components

GA109110G1, APEX2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA109110G2, APEX2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA109110G3, APEX2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001271748, NM_014481
UniProt ID Q9UBZ4
Synonyms APE2; APEXL2; XTH2; ZGRF2
Summary Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Nov 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN200320 APEX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200320BN APEX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200320LP APEX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200320RB APEX2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400320 APEX2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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