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B4GALT7 Human Gene Knockout Kit (CRISPR)

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SKU
KN200258BN
B4GALT7 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

Frequently Bought Together (3)

RC200258 B4GALT7 (Myc-DDK-tagged)-Human xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) (B4GALT7)
10 ug
$300.00
GE100003 pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
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TT300007S A non-viral, non-electroporation, non-liposomal transfection kit using engineered mammalian proteins, tailored for high-efficiency delivery into a wide range of primary cells and difficult to transfect cell lines such as immune cells, stem cells, and neuronal cells.
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Other products for "B4GALT7 or NM_007255"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Vector mBFP-Neo
Target Symbol B4GALT7
Locus ID 11285
Components

KN200258G1, B4GALT7 gRNA vector 1 in pCas-Guide CRISPR vector

KN200258G2, B4GALT7 gRNA vector 2 in pCas-Guide CRISPR vector

KN200258BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_007255
UniProt ID Q9UBV7
Synonyms EDSP1; XGALT1; XGPT1
Summary This gene is a member of the beta-1,4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. Mutations in this gene have been associated with the progeroid form of Ehlers-Danlos syndrome. provided by RefSeq, Oct 2009
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Documents
Resources
Other Versions
SKU Description Size Price
GA107780 B4GALT7 CRISPRa kit - CRISPR gene activation of human beta-1,4-galactosyltransferase 7 1 kit
$1,657.00
KN200258 B4GALT7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200258LP B4GALT7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200258RB B4GALT7 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400258 B4GALT7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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