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WDR79 (WRAP53) Human Gene Knockout Kit (CRISPR)

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SKU
KN200142
WRAP53 - human gene knockout kit via CRISPR, HDR mediated
  $1,657.00
4 Weeks*

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Other products for "WDR79 or NM_001143990"

Specifications
Specifications
Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Vector GFP-puro
Target Symbol WDR79
Locus ID 55135
Components

KN200142G1, WDR79 gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: GTCCGCATTTTTATTCATCG

KN200142G2, WDR79 gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: GGACTGCTGTCCTTCAGACC

KN200142D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

Homologous arm and GFP-puro sequences:

pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet

GTTGTATTCC TGAGTGCCTA TATCAGTGCT GGGTAGCAAG TAAGAGCTCG ATAATAAATA TTTTTTGAAT GAGGGAGACA GGTCTGAAGC CTGGAGAATG AGATGCAGAA GAGGTGCAAG ACCTGCTGCG CCCTCTGCAG GCGGCGGGGG GGCGGTGCAG GTGCTTTAAG AATTACCGCG GGACTCGGTA GGGGGAGCGT AGGCGCTTCT CGCCAAGATA GAAGCGTTCA GACTACAACT CCCAGCAGCC ACGAGGAGCC CTAGGGCTTG ATGGGAACGG GAAACCTTCT AACCTTTCAC GTCCCGGCTC CGCGGGTTCC GTGGGTCGCC CGCGAAATCT GATCCGGGAT GCGGCGGCCC AATCGGAAGG TGGACCGAAA TCCCGCGACA GCAAGAGGCC CGTAGCGACC CGCGGTGCTA AGGAACACAG TGCTTTCAAA AGAATTGGCG TCCGCTGTTC GCCTCTCCTC CCGGGAGTCT TCTGCCTACT CCCAGAAGAG GAGGGAAGCA CAGGTGGGTT TCTTTAGCTC TGCGTCGGAT CCCTGAGAAC TTCGAAGCCA TCCTGGCTGA GGCTAATCTC CGCTGTGCTT CCTCTGCAGT CCGCCTCCCG AAAGGGGGGA TCCGCCCCGG TTGTCCCCAG ATCCTGTGGC TGGCTCAGCT GTGTCCCAGG AGCTACGGGA GGGGGACCCA GTTTCTCTCT CCACTCCCCT GGAAACAGAG TTTGGTTCCC CTAGTGAGTT GAGTCCTCGA ATCGAGGAGC AAGAACTTTC TGAAAATACA AGCCTTCCTG CAGAAGAAGC AAACGGGAGC CTTTCTGAAG AAGAAGCGAA CGGGCCAGAG TTGGGGTCTG GAAAAGCCAT GGAAGATACC TCTGGGGAAC CCGCTGCAGA GGACGAGGGA GACACGTAAG TGGTGATGGC AGTGGAGTGT GGAGTCTGGG GAGATGAAGT GTGAGGTCGA TCTGTCCTCT GGTCCTGAGA CCCACTTCTC CAGGCCTCTG CCCCCTTTGC TTGGCGACCC AGGTTTATTG TCCCCCATCT TCCTTTCAGC GCTTGGAACT ACAGCTTCTC CCAGCTGCCT CGATTTCTCA GTGGTTCCTG GTCAGAGTTC AGCACCCAAC CTGAGAACTT CTTGAAAGGC TGTAAGTGGT AAGGATAACA ACGGGGCAGG GAGCTGACCA CCCCCGAGAT TTTCACTGTA

GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001143990, NM_001143991, NM_001143992, NM_018081
UniProt ID Q9BUR4
Synonyms DKCB3; TCAB1; WDR79
Summary This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. provided by RefSeq, Mar 2011
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Documents
Resources
Other Versions
SKU Description Size Price
GA110542 WRAP53 CRISPRa kit - CRISPR gene activation of human WD repeat containing antisense to TP53 1 kit
$1,657.00
KN200142BN WRAP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200142LP WRAP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200142RB WRAP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400142 WRAP53 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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