Human WDR79 (WRAP53) activation kit by CRISPRa

SKU
GA110542
WRAP53 CRISPRa kit - CRISPR gene activation of human WD repeat containing antisense to TP53
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol WRAP53
Locus ID 55135
Components

GA110542G1, WDR79 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA110542G2, WDR79 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA110542G3, WDR79 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001143990, NM_001143991, NM_001143992, NM_018081
UniProt ID Q9BUR4
Synonyms DKCB3; TCAB1; WDR79
Summary This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. provided by RefSeq, Mar 2011
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Documents
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Other Versions
SKU Description Size Price
KN200142 WRAP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200142BN WRAP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200142LP WRAP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN200142RB WRAP53 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN400142 WRAP53 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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