Mouse Spc25 activation kit by CRISPRa

SKU
GA206782
Spc25 CRISPRa kit - CRISPR gene activation of mouse SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Spc25
Locus ID 66442
Components

GA206782G1, Spc25 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206782G2, Spc25 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206782G3, Spc25 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001199123, NM_001199124, NM_025565
UniProt ID Q3UA16
Synonyms 2600017H08Rik; 2610205L13Rik; Spbc25
Summary This gene encodes a component of the kinetochore-associated NDC80 protein complex, which is required for the mitotic spindle checkpoint and for microtubule-kinetochore attachment. During meiosis in mouse, the protein localizes to the germinal vesicle and then is associated with the chromosomes following germinal vesicle breakdown. Knockdown of this gene in oocytes results in precocious polar body extrusion, chromosome misalignment and aberrant spindle formation. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2015
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Other Versions
SKU Description Size Price
KN516572 Spc25 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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