Spc25 Rabbit Polyclonal Antibody

SKU
TA363198
SPC25 Antibody - C-terminal region
  $585.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Reactivity Mouse
Antibody Host Rabbit
Clonality Polyclonal
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of mouse SPC25
Specificity Expected reactivity: Mouse
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration lot specific
Purification Affinity purified
Conjugation Unconjugated
Storage For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 19 kDa
Gene Name SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
Database Link
Background This gene encodes a component of the kinetochore-associated NDC80 protein complex, which is required for the mitotic spindle checkpoint and for microtubule-kinetochore attachment. During meiosis in mouse, the protein localizes to the germinal vesicle and then is associated with the chromosomes following germinal vesicle breakdown. Knockdown of this gene in oocytes results in precocious polar body extrusion, chromosome misalignment and aberrant spindle formation. Alternative splicing results in multiple transcript variants.
Synonyms 2600017H08Rik; AD024; hSpc25; MGC22228; SPBC25
Reference Data
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