Spc25 Rabbit Polyclonal Antibody

SKU TA363198

SPC25 Antibody - C-terminal region

Product Data

• Application: WB
• Reactivity: Mouse
• Antibody Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse SPC25
• Specificity: Expected reactivity: Mouse
• Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Shipping: Blue Ice
• Predicted Protein Size: 19 kDa
• Gene Name: SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
• Database Link:
  NP_001186052.1
  Q3UA16-2
• Background: This gene encodes a component of the kinetochore-associated NDC80 protein complex, which is required for the mitotic spindle checkpoint and for microtubule-kinetochore attachment. During meiosis in mouse, the protein localizes to the germinal vesicle and then is associated with the chromosomes following germinal vesicle breakdown. Knockdown of this gene in oocytes results in precocious polar body extrusion, chromosome misalignment and aberrant spindle formation. Alternative splicing results in multiple transcript variants.
• Synonyms: 2600017H08Rik; AD024; hSpc25; MGC22228; SPBC25

Reference Data