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Mouse Vhl activation kit by CRISPRa

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SKU
GA204595
Vhl CRISPRa kit - CRISPR gene activation of mouse von Hippel-Lindau tumor suppressor
  $1,657.00
4 Weeks*

Other products for "Vhl"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Vhl
Locus ID 22346
Components

GA204595G1, Vhl gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204595G2, Vhl gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204595G3, Vhl gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_009507
UniProt ID P40338
Synonyms Vhlh
Summary Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2 (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN318888 Vhl - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN318888BN Vhl - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN318888LP Vhl - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN318888RB Vhl - mouse gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN518888 Vhl - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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