Mouse Stat5a activation kit by CRISPRa

SKU GA204126

Stat5a CRISPRa kit - CRISPR gene activation of mouse signal transducer and activator of transcription 5A

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Stat5a
• Locus ID: 20850
• Components:

  GA204126G1, Stat5a gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA204126G2, Stat5a gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA204126G3, Stat5a gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001164062, NM_011488, NM_001362680
• UniProt ID: P42230
• Synonyms: AA959963; STAT5
• Summary: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.[UniProtKB/Swiss-Prot Function]