Stat5a Mouse Monoclonal Antibody [Clone ID: 5F6.F1]

SKU TA319572

Mouse monoclonal STAT5 phospho Y694 antibody (Phospho-specific)

Product Data

• Clone Name: 5F6.F1
• Application: IF, IHC, WB
• Recommended Dilution: ELISA: 1:20,000, WB: 1:500 - 1:2,000, IHC: 20-40 ug/ml, IF: 1:50-1:1000
• Reactivity: Human, Mouse, Rat
• Modification: Phospho-specific
• Antibody Host: Mouse
• Clonality: Monoclonal
• Immunogen: Anti-STAT5 phospho Y694 monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to residues surrounding Y694 of mouse STAT5a protein.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: signal transducer and activator of transcription 5A
• Database Link:
  NP_035618
  P42230
• Synonyms: MGF; STAT5
• Note: Signal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5a ?and Stat5β. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus. Ideal for Cancer, Chromatin & Nuclear Signaling and Signal Transduction research.

Reference Data