Mouse Numb activation kit by CRISPRa

SKU GA202993

Numb CRISPRa kit - CRISPR gene activation of mouse NUMB endocytic adaptor protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: Numb
• Locus ID: 18222
• Components:

  GA202993G1, Numb gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA202993G2, Numb gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA202993G3, Numb gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001136075, NM_001272055, NM_001272056, NM_010949, NR_073563, NR_073564
• UniProt ID: Q9QZS3
• Synonyms: Nb
• Summary: This gene encodes a conserved protein that is distributed asymmetrically during cell division in the developing embryo. The encoded protein participates in cell fate decisions by interacting with the Notch receptor. Loss of function of this gene results in severe defects in neural development and loss of viability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]