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Numb Goat Polyclonal Antibody

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SKU
TA302758
Goat Polyclonal Antibody against NUMB
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
In Stock*
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View other "Numb or NM_010949" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution ELISA: 1:16,000. WB: 0.3-1.0 µg/ml.
Reactivity Cow), Human, Mouse (Expected from sequence similarity: Dog
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence C-PFSSDLQKTFEIEL, from the C Terminus of the protein sequence according to NP_001005743.1; 001005744.1; NP_003735; NP_001005745.1.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name numb homolog (Drosophila)
Database Link
Background The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. provided by RefSeq
Synonyms h-Numb; S171
Reference Data
Protein Categories Intracellular Proteins
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Documents
Resources

file-alt Citations

The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1
Li, Fu, Zhang et al
Nat. Med. (2013)
Cited by 101
AI Summary: OriGene’s goat polyclonal anti-Numb antibody was used in this study to detect Numb protein levels, helping to elucidate Numb’s role in regulating intestinal cholesterol absorption through its interaction with NPC1L1.
Snippet: 69522, 1:1,000), mouse monoclonal anti-actin (Sigma, clone AC-15, 1:10,000), mouse monoclonal anti-CHC (BD Transduction Laboratories, clone 23, 1:10,000), rabbit monoclonal anti-Numb (Cell Signaling, C29G11, 1:1,000), goat polyclonal anti-Numb (Origene, ... Cite SaveSaving
WB
Showing 1-1 of 1 papers.
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