Human LIN28B activation kit by CRISPRa

SKU
GA118054
LIN28B CRISPRa kit - CRISPR gene activation of human lin-28 homolog B
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LIN28B
Locus ID 389421
Components

GA118054G1, LIN28B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA118054G2, LIN28B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA118054G3, LIN28B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001004317
UniProt ID Q6ZN17
Synonyms CSDD2
Summary The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. provided by RefSeq, Jun 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN213537 LIN28B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213537BN LIN28B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213537LP LIN28B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN213537RB LIN28B - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN413537 LIN28B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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