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Human GFRAL activation kit by CRISPRa

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SKU
GA118053
GFRAL CRISPRa kit - CRISPR gene activation of human GDNF family receptor alpha like
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA331490 Rabbit Polyclonal Anti-GFRAL Antibody
100 ul
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RC213001 GFRAL (Myc-DDK-tagged)-Human GDNF family receptor alpha like (GFRAL)
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Other products for "GFRAL"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GFRAL
Locus ID 389400
Components

GA118053G1, GFRAL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA118053G2, GFRAL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA118053G3, GFRAL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_207410
UniProt ID Q6UXV0
Synonyms bA360D14.1; C6orf144; GRAL; UNQ9356
Summary Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN413001 GFRAL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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