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Human STIMATE activation kit by CRISPRa

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SKU
GA117817
STIMATE CRISPRa kit - CRISPR gene activation of human STIM activating enhancer
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC208295 TMEM110 (Myc-DDK-tagged)-Human transmembrane protein 110 (TMEM110)
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Other products for "STIMATE"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol STIMATE
Locus ID 375346
Components

GA117817G1, STIMATE gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA117817G2, STIMATE gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA117817G3, STIMATE gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_198563
UniProt ID Q86TL2
Synonyms DKFZp667E1121; DKFZp779M0254; FLJ37613; FLJ42395; MGC52022
Summary Acts as a regulator of store-operated Ca(2+) entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679, PubMed:26644574). SOCE is a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:26322679). Acts by interacting with STIM1, promoting STIM1 conformational switch (PubMed:26322679). Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574). Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN408295 TMEM110 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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