Human CRB2 activation kit by CRISPRa

SKU GA117283

CRB2 CRISPRa kit - CRISPR gene activation of human crumbs cell polarity complex component 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CRB2
• Locus ID: 286204
• Components:

  GA117283G1, CRB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117283G2, CRB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117283G3, CRB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_173689, NR_104603
• UniProt ID: Q5IJ48
• Synonyms: FSGS9; VMCKD
• Summary: This gene encodes a member of a family of proteins that are components of the Crumbs cell polarity complex. In mammals, members of this family are thought to play a role in many cellular processes in early embryonic development. A similar protein in Drosophila determines apicobasal polarity in embryonic epithelial cells. Mutations in this gene are associated with focal segmental glomerulosclerosis 9, and with ventriculomegaly with cystic kidney disease. [provided by RefSeq, Aug 2016]