Human SKA3 activation kit by CRISPRa

SKU GA116596

SKA3 CRISPRa kit - CRISPR gene activation of human spindle and kinetochore associated complex subunit 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SKA3
• Locus ID: 221150
• Components:

  GA116596G1, SKA3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116596G2, SKA3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116596G3, SKA3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001166017, NM_145061
• UniProt ID: Q8IX90
• Synonyms: C13orf3; RAMA1
• Summary: This gene encodes a component of the spindle and kinetochore-associated protein complex that regulates microtubule attachment to the kinetochores during mitosis. The encoded protein localizes to the outer kinetechore and may be required for normal chromosome segregation and cell division. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]