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Human PYHIN1 activation kit by CRISPRa

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SKU
GA115718
PYHIN1 CRISPRa kit - CRISPR gene activation of human pyrin and HIN domain family member 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC213494 PYHIN1 (Myc-DDK-tagged)-Human pyrin and HIN domain family, member 1 (PYHIN1), transcript variant a1
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Other products for "PYHIN1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PYHIN1
Locus ID 149628
Components

GA115718G1, PYHIN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115718G2, PYHIN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115718G3, PYHIN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_152501, NM_198928, NM_198929, NM_198930
UniProt ID Q6K0P9
Synonyms IFIX
Summary The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Aug 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN410549 PYHIN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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