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Human UNC45B activation kit by CRISPRa

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SKU
GA115588
UNC45B CRISPRa kit - CRISPR gene activation of human unc-45 myosin chaperone B
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC223751 UNC45B (Myc-DDK-tagged)-Human unc-45 homolog B (C. elegans) (UNC45B), transcript variant 1
10 ug
$300.00

Other products for "UNC45B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol UNC45B
Locus ID 146862
Components

GA115588G1, UNC45B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115588G2, UNC45B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115588G3, UNC45B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001033576, NM_001267052, NM_001308281, NM_173167
UniProt ID Q8IWX7
Synonyms CMYA4; CTRCT43; SMUNC45; UNC-45B; UNC45
Summary This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN414543 UNC45B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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