Human EIF5AL1 activation kit by CRISPRa

SKU GA115452

EIF5AL1 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 5A like 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: EIF5AL1
• Locus ID: 143244
• Components:

  GA115452G1, EIF5AL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115452G2, EIF5AL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115452G3, EIF5AL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001099692
• UniProt ID: Q6IS14
• Synonyms: bA342M3.3; EIF5AP1
• Summary: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).[UniProtKB/Swiss-Prot Function]