Human NEURL2 activation kit by CRISPRa

SKU GA115414

NEURL2 CRISPRa kit - CRISPR gene activation of human neuralized E3 ubiquitin protein ligase 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NEURL2
• Locus ID: 140825
• Components:

  GA115414G1, NEURL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115414G2, NEURL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115414G3, NEURL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001278535, NM_080749, NR_074073
• UniProt ID: Q9BR09
• Synonyms: C20orf163; OZZ; OZZ-E3
• Summary: This gene encodes a protein that is involved in the regulation of myofibril organization. This protein is likely the adaptor component of the E3 ubiquitin ligase complex in striated muscle, and it regulates the ubiquitin-mediated degradation of beta-catenin during myogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2013]