Human STARD4 activation kit by CRISPRa

SKU
GA115226
STARD4 CRISPRa kit - CRISPR gene activation of human StAR related lipid transfer domain containing 4
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol STARD4
Locus ID 134429
Components

GA115226G1, STARD4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115226G2, STARD4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115226G3, STARD4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001308056, NM_001308057, NM_001308058, NM_001308059, NM_001308060, NM_001308061, NM_139164, NR_131752, NR_131753, NR_131754
UniProt ID Q96DR4
Summary Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 PubMed 12011452).supplied by OMIM, Mar 2008
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Documents
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Other Versions
SKU Description Size Price
KN423123 STARD4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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