Human GNPDA2 activation kit by CRISPRa

SKU GA115183

GNPDA2 CRISPRa kit - CRISPR gene activation of human glucosamine-6-phosphate deaminase 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GNPDA2
• Locus ID: 132789
• Components:

  GA115183G1, GNPDA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115183G2, GNPDA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115183G3, GNPDA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001270880, NM_001270881, NM_138335, NR_073094, NR_073095
• UniProt ID: Q8TDQ7
• Synonyms: GNP2; SB52
• Summary: The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]