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Human LYPD6B activation kit by CRISPRa

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SKU
GA115120
LYPD6B CRISPRa kit - CRISPR gene activation of human LY6/PLAUR domain containing 6B
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC207249 LYPD6B (Myc-DDK-tagged)-Human LY6/PLAUR domain containing 6B (LYPD6B)
10 ug
$289.00 $300.00

Other products for "LYPD6B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LYPD6B
Locus ID 130576
Components

GA115120G1, LYPD6B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115120G2, LYPD6B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115120G3, LYPD6B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001317002, NM_001317003, NM_001317004, NM_001317005, NM_001317006, NM_177964
UniProt ID Q8NI32
Synonyms CT116; LYPD7
Summary Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN407249 LYPD6B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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