Human LYPD6 activation kit by CRISPRa

SKU GA115119

LYPD6 CRISPRa kit - CRISPR gene activation of human LY6/PLAUR domain containing 6

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: LYPD6
• Locus ID: 130574
• Components:

  GA115119G1, LYPD6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115119G2, LYPD6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115119G3, LYPD6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001195685, NM_194317
• UniProt ID: Q86Y78
• Synonyms: MGC52057
• Summary: Members of the LY6 protein family (see SLURP1; MIM 606119), such as LYPD6, have at least one 80-amino acid LU domain that contains 10 conserved cysteines with a defined disulfide-bonding pattern (Zhang et al., 2010 [PubMed 19653121]).[supplied by OMIM, Apr 2010]