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Human PSMB11 activation kit by CRISPRa

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SKU
GA114782
PSMB11 CRISPRa kit - CRISPR gene activation of human proteasome subunit beta 11
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA334356 Rabbit Polyclonal Anti-PSMB11 Antibody
100 ul
$585.00
RC212390 PSMB11 (Myc-DDK-tagged)-Human proteasome (prosome, macropain) subunit, beta type, 11 (PSMB11)
10 ug
$300.00

Other products for "PSMB11"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PSMB11
Locus ID 122706
Components

GA114782G1, PSMB11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114782G2, PSMB11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114782G3, PSMB11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001099780
UniProt ID A5LHX3
Synonyms BETA5T
Summary Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7, and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM 600307), beta-2 (PSMB7; MIM 604030), and beta-5 (PSMB5; MIM 600306). Three additional subunits, beta-1i (PSMB9; MIM 177045), beta-2i (PSMB10; MIM 176847), and beta-5i (PSMB8; MIM 177046), are induced by gamma-interferon (IFNG; MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11, or beta-5t, is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al., 2007 PubMed 17540904).supplied by OMIM, Mar 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN412390 PSMB11 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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