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Human EXOSC6 activation kit by CRISPRa

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SKU
GA114660
EXOSC6 CRISPRa kit - CRISPR gene activation of human exosome component 6
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA343971 Rabbit Polyclonal Anti-EXOSC6 Antibody
100 ul
$525.00
RC208634 EXOSC6 (Myc-DDK-tagged)-Human exosome component 6 (EXOSC6)
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Other products for "EXOSC6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol EXOSC6
Locus ID 118460
Components

GA114660G1, EXOSC6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114660G2, EXOSC6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114660G3, EXOSC6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_058219
UniProt ID Q5RKV6
Synonyms EAP4; hMtr3p; MTR3; Mtr3p; p11
Summary This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN408634 EXOSC6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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