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Human TIRAP activation kit by CRISPRa

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SKU
GA114439
TIRAP CRISPRa kit - CRISPR gene activation of human TIR domain containing adaptor protein
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA306133 Rabbit Polyclonal TIRAP Antibody
100 ug
$640.00
RC207162 TIRAP (Myc-DDK-tagged)-Human toll-interleukin 1 receptor (TIR) domain containing adaptor protein (TIRAP), transcript variant 3
10 ug
$300.00

Other products for "TIRAP"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TIRAP
Locus ID 114609
Components

GA114439G1, TIRAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114439G2, TIRAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114439G3, TIRAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001039661, NM_001318776, NM_001318777, NM_052887, NM_148910
UniProt ID P58753
Synonyms BACTS1; Mal; MyD88-2; wyatt
Summary The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN407162 TIRAP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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