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Human PGAP3 activation kit by CRISPRa

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SKU
GA114273
PGAP3 CRISPRa kit - CRISPR gene activation of human post-GPI attachment to proteins 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA342058 Rabbit Polyclonal Anti-PGAP3 Antibody
100 ul
$585.00
RC202289 PGAP3 (Myc-DDK-tagged)-Human post-GPI attachment to proteins 3 (PGAP3)
10 ug
$300.00

Other products for "PGAP3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PGAP3
Locus ID 93210
Components

GA114273G1, PGAP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114273G2, PGAP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114273G3, PGAP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001291726, NM_001291728, NM_001291730, NM_001291732, NM_001291733, NM_033419
UniProt ID Q96FM1
Synonyms AGLA546; CAB2; hCOS16; PERLD1; PP1498
Summary This gene encodes a glycosylphosphatidylinositol (GPI)-specific phospholipase that primarily localizes to the Golgi apparatus. This ubiquitously expressed gene is predicted to encode a seven-transmembrane protein that removes unsaturated fatty acids from the sn-2 position of GPI. The remodeling of the constituent fatty acids on GPI is thought to be important for the proper association between GPI-anchored proteins and lipid rafts. The tethering of proteins to plasma membranes via posttranslational GPI-anchoring is thought to play a role in protein sorting and trafficking. Mutations in this gene cause an autosomal recessive form of neurologic hyperphosphatasia with cognitive disability (HPMRS4). Alternative splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Jul 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN402289 PGAP3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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